Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma

Source: Regenerative Injection Treatment in the Spine: Review and Case Series with Platelet Rich Plasma


Summary

5 patients were selected on the basis of a strict diagnostic criteria and inclusion factors. Each patient received a series of 3 PRP injections into the affected facet joints and surrounding ligaments using fluoroscopic or ultrasound-guidance. Relative immobilization with bracing was prescribed for 72 hours following the injections. Follow up examinations ranged from 6-12 months.


Case 1: 60% symptom improvement following 2nd injections, 100%improvement & return to sport at 6 months; Case 2: at least 30% symptom improvement following 1st injection, 60% improvement following the 2nd series, &1/10 VAS scale at 9 months; Case 3: at least 40% symptom improvement following 2nd injections, 2/10 VAS scale and improvement in functional status at 12 months; Case 4: 70% symptom improvement & increased functional status following 3rd injections; Case 5: 65-70% symptom improvement and increased functional status at 6-month follow-up.


Patients reported reduced fear and anxiety over inciting events, improved sleep, and decreased pain medication use. PRP injections can potentially represent a viable treatment option for spinal pain related to facet joints, capsules, and spinal ligaments.

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