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Steroid vs. PRP in Ultrasound-guided SJI for Chronic Lower Back Pain


Low back pain; methylprednisolone; platelet-rich plasma; prospective randomized open blinded end point study; sacroiliac joint injection; ultrasound-guided.


40 patients with chronic low back pain diagnosed with SIJ pathology were randomly allocated into 2 groups. Group S received 1.5 mL of methylprednisolone (40 mg/mL) and 1.5 mL of 2% lidocaine with 0.5 mL of saline, while Group P received 3 mL of leukocyte-free PRP with 0.5 mL of calcium chloride into ultrasound-guided SIJ injection. Visual analog scale (VAS) scores, Modified Oswestry Disability Questionnaire (MODQ) scores, Short Form (SF-12) Health Survey scores, and complications (if any) were evaluated at 2 weeks, 4 weeks, 6 weeks, and 3 months.

Intensity of pain was significantly lower in Group P at 6 weeks as compared to Group S.

The intra-articular PRP injection is an effective treatment modality in low back pain involving SIJ.

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